Strasbourg, France, July 24, 2017, 5:45 p.m. CET - Transgene (Euronext Paris: TNG), a biotech company that designs and develops viral-based immunotherapies, announces that new and encouraging preclinical data on its next generation armed engineered oncolytic virus platform have been published in Cancer Research. The publication presents key findings of Transgene’s latest improved vaccinia virus backbone expressing the Fcu1 gene, which is engineered to transform the non-cytotoxic pro-drug, flucytosine (5-FC), into 5-FU, a widely-used cancer chemotherapy.
These preclinical data further strengthen the preclinical data package of Transgene’s most advanced next generation oncolytic virus, TG6002, which is expected to enter the clinic in the coming months in patients with recurrent glioblastoma.
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